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Structure-activity relationships (Biochemistry) --- Biomolecules --- Analysis. --- Biomolecules.
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This volume includes comprehensive and up-to-date coverage of all nucleic acid-specific steps used in X-ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the book. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and thorough, Nucleic Acid Crystallography: Methods and Protocols presents protocols that are aimed at both researchers and students who are interested in the structural biology of DNA or RNA, alone or in complex with proteins or ligands. .
Nucleic acids. --- Nucleic Acid Chemistry. --- Polynucleotides --- Biomolecules
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This is an overview of single molecule physics, the study of both equilibrium and non-equilibrium properties at the single molecule level. It begins with an introduction to this fascinating science and includes a chapter on how to build the most popular instrument for single molecule biophysics, the total internal reflection fluorescence (TIRF) microscope. It concludes with the Poisson process approach to statistical mechanics, explaining how to relate the process to diverse areas and see how data analysis and error bars are integral parts of science.
Biophysics. --- Biomolecules. --- Biomolecules --- Biophysics --- Molecular Biology --- Biophysics. --- Instruments and instrumentation engineering. --- SCIENCE / Life Sciences / Biophysics. --- TECHNOLOGY & ENGINEERING / Measurement. --- Analysis. --- methods. --- methods.
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Nucleic acids --- Molecular dynamics. --- Computer simulation. --- Dynamics, Molecular --- Dynamics --- Polynucleotides --- Biomolecules
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Molecular biology. --- Molecular biology --- Experiments. --- Experiments --- History. --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology
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Biopolymers. --- Cellulose --- Microbiology. --- Bioactive polymers --- Biological polymers --- Natural polymers --- Naturally occurring polymers --- Biomolecules --- Polymers
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This book presents an overview of the most relevant protein knockdown techniques. Readers will find a description of the generation and use of recombinant human antibodies, ER intrabodies and peptides as well as a description of the working mechanism and potential of the inhibitory action of each of these molecules. The book will also describe the selection and activity of a number of phosphatases, aptamers and allosteric modulators, focusing on A G protein coupled receptors. The book starts with a chapter on the in silico prediction of target-inhibitor interactions. Key aspects of this book are: - Selection strategies for monoclonal and recombinant human antibodies - Selection strategies for ER intrabodies, peptides and aptamers - Examples of the most efficient inhibitors and their applications in protein biochemistry and cell biology - Antibodies for cancer therapy and inhibitors of angiogenesis. The book will be of great interest to scientists and students working in the life sciences on all areas related to protein biology. The variety of methods to modulate the activities of specific proteins which are introduced here will be of great benefit to the reader who is interested in general protein research or to readers who have very specific protein related questions.
Medicine. --- Immunology. --- Biomedicine. --- Proteins --- Synthesis --- Inhibitors. --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Immunobiology --- Life sciences --- Serology
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"Biopolymer Composites in Electronics examines the current state-of-the-art in the electronic application based on biopolymer composites. Covering the synthesis, dispersion of fillers, characterization and fabrication of the composite materials, the book will help materials scientists and engineers address the challenges posed by the increased use of biopolymeric materials in electronic applications. The influence of preparation techniques on the generation of micro, meso, and nanoscale fillers, and the effect of filler size and dispersion on various biopolymers are discussed in detail. Applications covered include sensors, actuators, optics, fuel cells, photovoltaics, dielectrics, electromagnetic shielding, piezoelectrics, flexible displays, and microwave absorbers. Characterization techniques are discussed and compared, enabling scientists and engineers to make the correct choice of technique." --
Biopolymers. --- Bioactive polymers --- Biological polymers --- Natural polymers --- Naturally occurring polymers --- Biomolecules --- Polymers
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Proteins. --- Intermediate filament proteins. --- Fibroblast intermediate filament proteins --- Cytoplasmic filaments --- Cytoskeletal proteins --- Proteids --- Biomolecules --- Polypeptides --- Proteomics
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